HPLC certificate of analysis pending — typically published within a month of batch receipt.
Research at a glance
Ipamorelin is a synthetic pentapeptide characterised in the literature as a selective agonist of the growth hormone secretagogue receptor 1a (ghrelin receptor). Preclinical work has studied it chiefly in animal models of feeding, reproductive endocrinology, and gastrointestinal motility, alongside analytical and clinical investigations in humans. The evidence base is predominantly animal and in vitro, with a small number of controlled human studies; broader controlled human data remain limited.
In a cichlid fish model (Oreochromis mossambicus), administration of ipamorelin acetate over 21 days was associated with dose-dependent increases in food intake and in spermatocyte and spermatid counts, alongside elevated androgen receptor expression and serum luteinizing hormone and 11-ketotestosterone, within a study of the hypothalamic-pituitary-testicular axis.[1]
AnimalPreliminaryIn a randomized, double-blind, placebo-controlled phase 2 proof-of-concept trial in adults undergoing bowel resection, intravenous ipamorelin was evaluated for safety and for time to tolerance of a standardized solid meal in the setting of postoperative ileus.[2]
HumanEmergingIn a human urinary study following nasal administration, ipamorelin was reported to metabolise extensively and to be excreted as a set of parent compound and metabolites, with the Ipamorelin (1-4) free acid identified by nano-liquid chromatography–high resolution mass spectrometry in the context of anti-doping analysis.[3]
HumanPreliminary
What the research does not show
The human evidence identified in this search is limited in scale; larger controlled trials establishing exposure and long-term safety in humans are not yet available.
Handling & storage
Lyophilized (sealed): store at −20 °C, protected from light.
Reconstituted: store at 2–8 °C; use within a few weeks.
Avoid repeated freeze–thaw cycles and prolonged light exposure.
Reconstitution reference — concentration calculator
Enter a volume of bacteriostatic water to see the resulting concentration of the reconstituted vial.
A concentration reference for lab handling — not a dose or administration instruction.
Studied alongside
Compounds investigated together in the research literature, and how they compare. Shared research focus is marked *; the rest is where they differ.
Ipamorelin and CJC-1295 are frequently co-studied: both are examined in growth research, and they recur together across the cited reports. The pairing reflects a shared research context and overlapping study areas rather than a demonstrated combined interaction.
Compare the two compounds
References
References (6)
- 1.Gouda M et al., Animal reproduction science 2024Animal reproduction science, 2024· Animal
- 2.Beck DE et al., International journal of colorectal disease 2014International journal of colorectal disease, 2014· Human
- 3.Semenistaya E et al., Drug testing and analysis 2015Drug testing and analysis, 2015· Human
- 4.Mavrych V et al., Frontiers in aging 2026Frontiers in aging, 2026· Review
- 5.Mayfield CK et al., The American journal of sports medicine 2026The American journal of sports medicine, 2026· Review
- 6.Rahman OF et al., Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews 2026Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews, 2026· Review
Sources last reviewed 19 Jul 2026